Cover photo for Karen S. Isler's Obituary
Karen S. Isler Profile Photo
1960 Karen 2025

Karen S. Isler

April 12, 1960 — October 24, 2025

Gaffney, SC

Karen Sellars Isler 65 of Gaffney passed away peacefully and in the presence of her loving family on October 24, 2025.

Karen was born to the late Ruth Childers and Raymond (Mildred) Sellars. She was known as a loving and dedicated wife to Wayne Isler Sr. for 47 years. She was a devoted mother to Christina (Jammie) Gossett and Wayne (April) Isler Jr. Four grandchildren Kayla (Brandon) Layton, Cody Isler, Justin Gossett, Breanna (Tyler) Sturgill, four great grandchildren Brooklynn, Riley, Harrison, Baby Sturgill, due May 2026 And her spoiled, loving companion Poncho. Brothers Jeffrey Sellars and Mike Williams and sister Michelle Loeskann. We will forever hold her memories close to our hearts forever.

The family will receive Friends and Service Monday, October 27 from 3 to 4 at Mayo First Baptist Church.

The family will be at their respective homes.

Harris-Nadeau Mortuary & Crematory

Chesnee, SC.

To order memorial trees or send flowers to the family in memory of Karen S. Isler, please visit our flower store.

Service Schedule

Upcoming Services

Celebration of Life

Monday, October 27, 2025

3:00 - 4:00 pm (Eastern time)

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Mayo First Baptist Church

190 Mayo Road, Mayo, SC 29368

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